The problem is most likely a mix of static buildup and accidental input rejection algorithms. As algorithms ‘learn’ your taps and swipes, the occasional spurious static electricity confuses the machine learning model. As you continue to use your iPad, the model mistakenly learns to ignore some normal swipes and taps. Hard reset (hold Home+Sleep button) alleviates the problem temporarily. Limiting refresh rate, helps temporarily as well. These problems seem to appear more frequently on larger 120hz devices due to necessarily more aggressive accidental/spurious input rejection. Apple should be able to address this via software update. The static electricity problem seems more pronounced in high humidity, but this is anecdotal.